N-Acetyl Semax Amidate Product Description
N-Acetyl Semax Amidate is a stabilized synthetic peptide variant engineered through N-terminal acetylation and C-terminal amidation to resist enzymatic degradation and extend biological activity. This modification replaces the original peptide’s terminal carboxylic acid (-COOH) with an amide group (-NH₂), enhancing its stability.
Structurally defined as Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH₂, it demonstrates prolonged half-life (~30 minutes longer than standard Semax) and increased neuroprotective efficacy, modulating neurotransmitters like serotonin and dopamine and upregulating BDNF expression. Preclinical studies highlight its potential in cognitive enhancement, neuroregeneration, and therapeutic applications for stroke or neurodegenerative disorders.
Peptide Information
Property Value
Peptide Sequence Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
Molecular Formula C37H51N9O10S
Molecular Weight 813.9 g/mol
CAS Number 80714-61-0
PubChem CID 9811102
Synonyms Semax, 80714-61-0, ACTH (4-7), Pro-Gly-Pro-, MEHFPGP, Met-Glu-His-Phe-Pro-Gly-Pro
Semax Peptide Structure
Semax.png
Source: PubChem
99%+ Purity, Third Party Tested
Independently verified by three separate certified laboratories. COAs available pre-purchase.
GMP Manufacturing Standards
Synthesized in USA-registered facilities following Good Manufacturing Practices. Full chain of custody documentation.
Best In Class Fulfillment
Same-day shipping on orders before 12 PM PT. Free standard domestic shipping on orders over $400.
Zero Fillers or Additives
Pure active compounds only. Independently verified composition for reliable in vitro studies.
Scientific Reviewer
Scientifically reviewed by Dr. Ky H. Le, MD. Dr. Le is a board-certified family medicine physician with over 20 years of clinical experience. Dr. Le validates the scientific accuracy of all technical content and research citations.
Disclaimer: For Research Purposes Only
This content is provided strictly for research purposes and does not constitute an endorsement or recommendation for the non-laboratory application or improper handling of peptides designed for research. The information, including discussions about specific peptides and their researched benefits, is presented for informational purposes only and must not be construed as health, clinical, or legal guidance, nor an encouragement for non-research use. Peptides described here are solely for use in structured scientific study by authorized individuals. We advise consulting with research experts, medical practitioners, or legal counsel prior to any decisions about obtaining or utilizing these peptides. The expectation of responsible, ethical utilization of this information for legitimate investigative and scholarly objectives is paramount. This notice is dynamic and governs all provided content on research peptides.




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